![]() The three classic symptoms of Horner's syndrome (sometimes called Horner syndrome or Horners syndrome) are: Brain disorders associated with anisocoria include strokes, hemorrhage (spontaneous or due to head injury) and, less commonly, certain tumors or infections. People with nervous system disorders that cause anisocoria often also have a drooping eyelid, double vision and/or strabismus. One of the most significant of these is Horner's syndrome. A number of conditions that damage nerves in the brain or spinal cord can cause anisocoria. But it can be associated with eye trauma (including trauma caused by complicated cataract surgery), lack of blood flow (ischemia) or an infection. In most cases, the cause of Adie's pupil is unknown. The affected pupil also does not react to light. This benign condition (also called Adie's pupil, tonic pupil or Adie's syndrome) typically causes one pupil to be noticeably bigger than the other. Iritis (anterior uveitis) can cause anisocoria that usually is accompanied by eye pain.Īdie's tonic pupil. For example, pilocarpine eye drops used to treat glaucoma may cause the pupil of the treated eye to be smaller than the other pupil. For example, read about David Bowie's eyes below.Ĭertain eye medications. ![]() Causes of significant anisocoria (one pupil bigger than the other by more than 1.0 mm) include:Įye trauma. Significant anisocoria, however, can have a number of causes, and some can be medical problems. Other research also suggests approximately 20% of the general population has mild benign anisocoria. The prevalence of anisocoria did not vary with the time of day or from day to day nor was it influenced by the sex, age or eye colour of the subject. At any given photo session, a fairly constant number of subjects (19%) showed this amount of mild anisocoria. Photographs were taken in the morning and afternoon each day.įifty-two of the subjects (41%) had an anisocoria of 0.4 mm or more at one time or another during these five days. In one study of the prevalence of anisocoria, researchers photographed the pupils of 128 normal subjects in dim light for five consecutive days. Generally, these cases of anisocoria where one pupil is bigger than the other by less than 1.0 mm with no apparent cause are called simple anisocoria, benign anisocoria or physiologic anisocoria. Many cases of mild anisocoria are normal and do not have any underlying pathology or history of trauma. One pupil may be bigger than normal ( dilated), or one pupil may be smaller than normal (constricted), resulting in different-sized pupils. Anisocoria definitionĪnisocoria ("an-eye-so-CORE-ee-ah") means you have unequal pupils. Does one pupil look noticeably larger or smaller than the other? If so, you may have anisocoria.
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